Allyl alcohol and garlic (Allium sativum) extract produce oxidative stress in Candida albicans
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منابع مشابه
Allyl alcohol and garlic (Allium sativum) extract produce oxidative stress in Candida albicans.
Both the growth and respiration of Candida albicans are sensitive to extracts of Allium sativum and investigations into the anticandidal activities are now focussing on the purified constituents to determine the targets of inhibition. Of particular interest is allyl alcohol (AA), a metabolic product that accumulates after trituration of garlic cloves. Putative targets for AA were investigated b...
متن کاملAllium sativum (garlic) inhibits lipid synthesis by Candida albicans.
The effect of aqueous garlic extract on the macromolecular synthesis of Candida albicans was studied. Protein and nucleic acid syntheses were inhibited to the same extent as growth, but lipid synthesis was completely arrested. Blockage of lipid synthesis is likely an important component of the anticandidal activity of garlic.
متن کاملGarlic (Allium sativum)
Overview Garlic’s current principal medicinal uses are to prevent and treat cardiovascular disease by lowering blood pressure and cholesterol, as an antimicrobial, and as a preventive agent for cancer. The active constituents are several complex sulfur-containing compounds that are rapidly absorbed, transformed and metabolized. Pooled data from numerous randomized trials suggest that garlic low...
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Introduction. Garlic (Allium sativum) is believed to have been originated from Central Asia over 6,000 years ago, but has spread to almost everywhere long time ago. Garlic is the edible bulb of the lily family, Liliaceae. It is a relative of the onion and leek, and other related species containing the aromatic sulfur-based compounds, which contribute to the characteristic odor and taste, as wel...
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Thirty strains of mycobacteria, consisting of 17 species, were inhibited by various concentrations of garlic extract incorporated in Middlebrook 7H10 agar. The concentration required ranged from a low of 1.34 mg/ml to a high of 3.35 mg/ml of media. When there were multiple strains of a species, a mean inhibitory concentration was determined for that species. Six strains of Mycobacterium tubercu...
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ژورنال
عنوان ژورنال: Microbiology
سال: 2005
ISSN: 1350-0872,1465-2080
DOI: 10.1099/mic.0.28095-0